Health

Real world evidence generation

We work with our clients to generate rigorous and impactful real world evidence. Our approach is grounded in high quality science, combining expertise in epidemiology, statistics and real world health data with modern data science methods and ways of working.

Our team works closely with clients to navigate and address the increasingly complex need for real evidence from healthcare professionals, payers and HTA bodies, regulators and policy makers.

How the life sciences sector can address the greatest health challenges and reduce inequalities

Health is one of our most untapped opportunities for prosperity and happiness, as both individuals and society. Yet these opportunities are not shared equally. The life sciences sector has a unique opportunity to actively reduce health inequalities, which we explore in our report.

Explore the report
ONS Health Index Explorer

See the health index in your area, how it has changed over time and compares to other local authorities.

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Going swimmingly or treading water?

Read our on point paper which explores whether the elective recovery plan is bringing down NHS waiting lists.

Read the report
NHS waiting list tracker

Explore our interactive tracker to see how waiting lists for NHS services vary across England.

Start here

We use both traditional and cutting-edge real-world data sources

We specialise in RWE (real-world evidence) studies using electronic health records, administrative data, biobanks, registries, claims data and other sources of real-world data (RWD). Our team has expertise in sourcing and partnering with real-world data sources around the world, including leading UK RWD sources (e.g. Discover, CPRD, UK Biobank, HES, NCRAS).

As well as expertise in traditional RWD sources, we also work at the cutting edge of RWD sources and RWE methodologies, including electronic social care records and clinico-genomic data.

We support our clients with RWE design and execution across the medicines development lifecycle, including:

Burden of illness and other types of payer evidence studies
Comparative effectiveness
Natural history of disease
Pharmacovigilance and drug safety
Drug utilisation
Advanced epidemiological study designs such as real-world comparators
Development and validation of statistical and AI/ML models
Impact evaluations

How evidence is communicated is critical in making sure that key messages are shared accurately and with impact. Our team has authored hundreds of peer-reviewed publications across many therapy areas, including in leading journals (The Lancet, The BMJ, PLOS Medicine etc), using innovative data visualisations and technology to communicate evidence.